Across TCGA patient cohorts, ZCWPW2 mutation is significantly associated with the RNA expression of many other genes, with 705 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZCWPW2-associated genes across cancer lineages are RNF11P1, LARP1BP3, and RN7SKP181. Each is linked with ZCWPW2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZCWPW2-to-partner and partner-to-ZCWPW2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZCWPW2→partner) and Y-score (partner→ZCWPW2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNF11P1 →	+0.091	+4.234	.005	.008	3	3
STAD	LARP1BP3 →	+0.140	+3.311	.003	.008	3	3
UCEC	RN7SKP181 →	+0.107	+2.674	.001	.006	3	3
UCEC	MTCYBP12 →	+0.381	+2.286	<.001	.008	3	3
CESC	MRPS16P1 →	+0.062	+4.812	<.001	.006	3	2
CESC	CKAP2P1 →	+0.031	+4.364	.002	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 705 associations by consensus.

Exploration

ZCWPW2 survival (RNA) · tumor vs normal (RNA) · all ZCWPW2 data types