ZCWPW2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZCWPW2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZCWPW2-associated genes across cancer lineages are OR4M1 and ACER1. Each is linked with ZCWPW2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZCWPW2-to-partner and partner-to-ZCWPW2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZCWPW2→partner) and Y-score (partner→ZCWPW2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADOR4M1 →+0.010+5.266<.001.00131
LARGE_INTESTINEACER1 →+0.079+3.823.005.00631
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration