ZCWPW1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZCWPW1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZCWPW1-associated genes across cancer lineages are ACER1. Each is linked with ZCWPW1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZCWPW1-to-partner and partner-to-ZCWPW1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACER1 grouped by ZCWPW1-low versus ZCWPW1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZCWPW1→partner) and Y-score (partner→ZCWPW1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEACER1 →+0.103+4.145<.001.00131
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

ACER1 by ZCWPW1 expression — LARGE_INTESTINE

Box plot of ACER1 in ZCWPW1-low vs ZCWPW1-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration