ZCCHC9

Across TCGA patient cohorts, ZCCHC9 mutation is significantly associated with the RNA expression of many other genes, with 688 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZCCHC9-associated genes across cancer lineages are TRAJ19, HMGN2P32, and RN7SL83P. Each is linked with ZCCHC9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZCCHC9-to-partner and partner-to-ZCCHC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ19 grouped by ZCCHC9-low versus ZCCHC9-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZCCHC9→partner) and Y-score (partner→ZCCHC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TRAJ19 →	+0.667	+3.588	.001	.007	3	2
COAD	HMGN2P32 →	+1.031	+3.589	<.001	.009	3	2
COAD	RN7SL83P →	+0.366	+4.392	<.001	.006	3	2
BLCA	LINC01148 →	+0.057	+5.106	<.001	.008	3	2
UCEC	TRGJP2 →	+0.700	+2.888	<.001	<.001	3	2
UCEC	IGHD2-15 →	+1.530	+1.982	.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 688 associations by consensus.

TRAJ19 by ZCCHC9 expression — COAD

Explore this box plot interactively →