ZCCHC9

Across TCGA cell cohorts, ZCCHC9 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,852 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ZCCHC9-associated GO terms across cancer lineages are Regulation of rRNA processing, Regulation of centriole elongation, and Protein localization to site of double-strand break. Each is linked with ZCCHC9 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZCCHC9-to-partner and partner-to-ZCCHC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of rRNA processing grouped by ZCCHC9-low versus ZCCHC9-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZCCHC9→partner) and Y-score (partner→ZCCHC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of rRNA processing →	+0.095	+0.889	<.001	<.001	3	10
OVARY	Regulation of centriole elongation →	+0.089	+0.730	<.001	<.001	3	9
BONE	Protein localization to site of double-strand break →	+0.087	+0.836	.001	.001	3	9
STOMACH	Protein branched polyubiquitination →	+0.114	+0.655	.002	.001	3	8
LIVER	tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation →	+0.155	+0.549	<.001	.002	2	9
LARGE_INTESTINE	Target-directed miRNA degradation →	+0.089	+0.483	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,852 associations by consensus.

Regulation of rRNA processing by ZCCHC9 expression — LUNG_SCLC

Explore this box plot interactively →