ZCCHC7

Across TCGA pan-cancer cohorts, ZCCHC7 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ZCCHC7 data layer compared with 22 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher ZCCHC7 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZCCHC7 expression acts as an unfavorable survival marker.

LSCC and PDAC are the cancer types where ZCCHC7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Quartile	All	0.172	0.859	.004	12	view →
PDAC	DFS	Tertile	II,III,IV	0.413	0.710	.039	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

ZCCHC7–LSCC (DFS)

Open the LSCC breakdown →