ZCCHC7

Across TCGA cell cohorts, ZCCHC7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,125 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZCCHC7-associated GO terms across cancer lineages are snRNA catabolic process, CUT catabolic process, and sno(s)RNA catabolic process. Each is linked with ZCCHC7 in more than 19 cancer types. Because this analysis shows association rather than direction, both ZCCHC7-to-partner and partner-to-ZCCHC7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, snRNA catabolic process grouped by ZCCHC7-low versus ZCCHC7-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZCCHC7→partner) and Y-score (partner→ZCCHC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	snRNA catabolic process →	+0.129	+0.825	<.001	<.001	3	20
BLOOD_Lymphoma	CUT catabolic process →	+0.154	+1.534	<.001	<.001	3	20
LUNG_NSCLC_LUSC	sno(s)RNA catabolic process →	+0.154	+0.975	.001	.002	3	17
LUNG_NSCLC_LUSC	Nuclear mRNA surveillance →	+0.129	+0.954	<.001	<.001	3	16
LIVER	tRNA surveillance →	+0.123	+0.740	.008	.009	2	16
LARGE_INTESTINE	tRNA decay →	+0.106	+0.624	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,125 associations by consensus.

snRNA catabolic process by ZCCHC7 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →