ZCCHC3

Across TCGA patient cohorts, ZCCHC3 protein abundance is significantly associated with the RNA expression of many other genes, with 15,077 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZCCHC3-associated genes across cancer lineages are CSNK2A1, ZNF133, and MGME1. Each is linked with ZCCHC3 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZCCHC3-to-partner and partner-to-ZCCHC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZCCHC3 versus CSNK2A1 in COAD, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZCCHC3→partner) and Y-score (partner→ZCCHC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CSNK2A1 →	+0.650	+0.612	<.001	<.001	3	7
OV	ZNF133 →	+0.797	+0.486	<.001	.009	3	7
LSCC	MGME1 →	+0.630	+0.577	<.001	<.001	3	7
LSCC	MCM8 →	+0.777	+0.636	<.001	<.001	3	7
UCEC	ZNF343 →	+0.746	+0.405	<.001	<.001	3	7
LUAD	GINS1 →	+0.808	+0.477	.001	.002	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,077 associations by consensus.

ZCCHC3 vs CSNK2A1 — COAD

Explore this scatter interactively →