ZCCHC3

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZCCHC3 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible ZCCHC3-associated genes across cancer lineages are Adipocytes and Monocytes. Each is linked with ZCCHC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZCCHC3-to-partner and partner-to-ZCCHC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by ZCCHC3-low versus ZCCHC3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZCCHC3→partner) and Y-score (partner→ZCCHC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADAdipocytes →+0.040+3.431.015.02031
LIHCMonocytes →+0.014+5.305.007.04831
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Adipocytes by ZCCHC3 expression — COAD

Box plot of Adipocytes in ZCCHC3-low vs ZCCHC3-high samples in COAD.

Explore this box plot interactively →

Exploration