ZCCHC24

Across TCGA pan-cancer cohorts, ZCCHC24 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ZCCHC24 data layer compared with 25 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher ZCCHC24 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZCCHC24 expression acts as an unfavorable survival marker.

STAD and UCEC are the cancer types where ZCCHC24 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	II,III,IV	0.215	0.660	.019	18	view →
UCEC	OS	Median	IV	0.225	0.772	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

ZCCHC24–STAD (OS)

Open the STAD breakdown →