ZCCHC2

Across TCGA patient cohorts, ZCCHC2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,899 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ZCCHC2-associated genes across cancer lineages are CNDP2, NARS1, and STAT1. Each is linked with ZCCHC2 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZCCHC2-to-partner and partner-to-ZCCHC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZCCHC2 versus CNDP2 in HNSC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZCCHC2→partner) and Y-score (partner→ZCCHC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CNDP2 →	+1.243	+0.550	.005	.003	3	4
HNSC	NARS1 →	+0.605	+0.423	.007	<.001	3	4
HNSC	STAT1 →	+2.139	+0.636	<.001	.001	3	4
HNSC	CCR8 →	+0.915	+0.446	.003	<.001	3	4
HNSC	CASP5 →	+1.613	+0.549	<.001	<.001	2	4
UCEC	BBS9 →	-0.505	-0.449	.002	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,899 associations by consensus.

ZCCHC2 vs CNDP2 — HNSC

Explore this scatter interactively →