ZC3HC1

Across TCGA cell cohorts, ZC3HC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,855 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZC3HC1-associated GO terms across cancer lineages are DNA-templated transcription termination, Positive regulation of isotype switching to IgG isotypes, and XMP metabolic process. Each is linked with ZC3HC1 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZC3HC1-to-partner and partner-to-ZC3HC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription termination grouped by ZC3HC1-low versus ZC3HC1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3HC1→partner) and Y-score (partner→ZC3HC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DNA-templated transcription termination →	+0.124	+1.089	<.001	<.001	3	15
BLOOD_Lymphoma	Positive regulation of isotype switching to IgG isotypes →	+0.170	+0.731	<.001	<.001	3	15
PANCREAS	XMP metabolic process →	+0.166	+0.786	.001	.004	3	14
PANCREAS	XMP biosynthetic process →	+0.166	+0.786	.001	.004	3	14
PANCREAS	'de novo' XMP biosynthetic process →	+0.166	+0.786	.001	.004	3	14
UPPER_AERODIGESTIVE_TRACT	'de novo' IMP biosynthetic process →	+0.149	+0.837	.002	.003	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,855 associations by consensus.

DNA-templated transcription termination by ZC3HC1 expression — SOFT_TISSUE

Explore this box plot interactively →