ZC3HC1

Across TCGA cell cohorts, ZC3HC1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZC3HC1-associated genes across cancer lineages are OR2AP1 and OR14A16. Each is linked with ZC3HC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZC3HC1-to-partner and partner-to-ZC3HC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2AP1 grouped by ZC3HC1-low versus ZC3HC1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3HC1→partner) and Y-score (partner→ZC3HC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR2AP1 →	+0.012	+5.539	<.001	.003	3	1
BLOOD_Leukemia	OR14A16 →	+0.226	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR2AP1 by ZC3HC1 expression — BLOOD_Leukemia

Explore this box plot interactively →