ZC3HAV1

Across TCGA pan-cancer cohorts, ZC3HAV1 Mutation is linked to patient survival in 9 of 34 cancer types, making it a survival-associated ZC3HAV1 data layer compared with 25 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher ZC3HAV1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZC3HAV1 expression acts as an unfavorable survival marker, although some lineages such as READ and UCEC show a favorable association.

BRCA, COAD, and LUAD are the cancer types where ZC3HAV1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Median	All	0.543	0.904	<.001	32	view →
COAD	OS	Median	III,IV	0.056	0.783	<.001	25	view →
LUAD	DFS	Median	All	0.200	0.815	<.001	21	view →
STAD	OS	Median	All	0.209	0.584	.020	9	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
LIHC	DFS	Median	All	0.044	0.553	<.001	6	view →
SKCM	OS	Median	III,IV	0.572	0.849	.028	4	view →
READ	DFS	Median	II,III,IV	1.000	0.433	.045	2	view →
UCEC	OS	Median	All	0.955	0.864	.046	2	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

ZC3HAV1–BRCA (DFS)

Open the BRCA breakdown →