ZC3HAV1

Across TCGA cell cohorts, ZC3HAV1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,502 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZC3HAV1-associated GO terms across cancer lineages are Negative regulation of viral genome replication, Positive regulation of interferon-beta production, and Negative regulation of viral process. Each is linked with ZC3HAV1 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZC3HAV1-to-partner and partner-to-ZC3HAV1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of viral genome replication grouped by ZC3HAV1-low versus ZC3HAV1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3HAV1→partner) and Y-score (partner→ZC3HAV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of viral genome replication →	+0.190	+0.900	<.001	<.001	3	15
LARGE_INTESTINE	Positive regulation of interferon-beta production →	+0.086	+1.209	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of viral process →	+0.147	+0.831	<.001	<.001	3	14
BREAST	Regulation of viral process →	+0.139	+1.072	<.001	<.001	3	14
BREAST	Defense response to virus →	+0.078	+0.973	.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Antiviral innate immune response →	+0.086	+0.907	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,502 associations by consensus.

Negative regulation of viral genome replication by ZC3HAV1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →