ZC3HAV1

Across TCGA cell cohorts, ZC3HAV1 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ZC3HAV1-associated genes across cancer lineages are GJA10, OR13D1, and FEZF2. Each is linked with ZC3HAV1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZC3HAV1-to-partner and partner-to-ZC3HAV1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GJA10 grouped by ZC3HAV1-low versus ZC3HAV1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3HAV1→partner) and Y-score (partner→ZC3HAV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	GJA10 →	+0.026	+3.930	<.001	.003	3	3
SKIN	OR13D1 →	+0.017	+3.930	.003	.003	3	2
LUNG_NSCLC_LUAD	FEZF2 →	+0.013	+4.189	<.001	.002	3	2
BLOOD_Myeloma	KRTAP12-1 →	+0.066	+4.807	<.001	.006	3	1
BLOOD_Myeloma	KIR2DS4 →	+0.023	+4.807	<.001	.006	3	1
OVARY	CST11 →	+0.100	+5.807	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

GJA10 by ZC3HAV1 expression — SKIN

Explore this box plot interactively →