Across TCGA patient cohorts, ZC3H6 protein abundance is significantly associated with the RNA expression of many other genes, with 6,474 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZC3H6-associated genes across cancer lineages are ZNF25, PDCL3P4, and AQP9. Each is linked with ZC3H6 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZC3H6-to-partner and partner-to-ZC3H6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H6→partner) and Y-score (partner→ZC3H6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNF25 →	+0.470	+0.256	.001	.001	3	4
BRCA	PDCL3P4 →	+0.711	+0.221	<.001	<.001	3	4
BRCA	AQP9 →	-0.907	-0.218	<.001	.001	3	3
BRCA	TMEM106B →	+0.504	+0.237	<.001	<.001	3	3
BRCA	KIAA1191 →	+0.420	+0.235	<.001	<.001	3	3
LUAD	ZNF599 →	+0.459	+0.314	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,474 associations by consensus.

Exploration

ZC3H6 survival (RNA) · tumor vs normal (RNA) · all ZC3H6 data types