ZC3H6

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZC3H6 mutation is significantly associated with the RNA expression of many other genes, with 3,115 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZC3H6-associated genes across cancer lineages are TSPY26P, KRTAP4-3, and CCL5. Each is linked with ZC3H6 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZC3H6-to-partner and partner-to-ZC3H6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H6→partner) and Y-score (partner→ZC3H6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTSPY26P →-0.529-2.129.006.00333
CESCKRTAP4-3 →+0.081+5.584<.001.00132
UCECCCL5 →+1.238+2.679<.001<.00132
UCECLINC02084 →+0.468+1.769<.001.00332
UCECIGKV2-40 →+0.163+2.046.001.00132
UCECTMEM269 →+0.188+1.787<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,115 associations by consensus.

Exploration