Across TCGA cell cohorts, ZC3H6 mutation is significantly associated with the RNA expression of many other genes, with 175 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZC3H6-associated genes across cancer lineages are CTDNEP1, FAM124A, and NF2. Each is linked with ZC3H6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZC3H6-to-partner and partner-to-ZC3H6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H6→partner) and Y-score (partner→ZC3H6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CTDNEP1 →	+0.605	+3.212	<.001	.006	3	2
BLOOD_Leukemia	FAM124A →	+0.806	+3.411	<.001	.003	3	2
BLOOD_Leukemia	NF2 →	+0.509	+3.351	.002	.003	3	2
URINARY_TRACT	SLC32A1 →	+0.016	+5.087	<.001	.004	3	1
LARGE_INTESTINE	R3HCC1 →	+0.723	+3.212	.007	.006	2	2
LARGE_INTESTINE	KDSR →	+0.821	+3.212	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 175 associations by consensus.

Exploration

ZC3H6 survival (RNA) · tumor vs normal (RNA) · all ZC3H6 data types