ZC3H15

Across TCGA pan-cancer cohorts, ZC3H15 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZC3H15 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ZC3H15 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ZC3H15 expression acts as an unfavorable survival marker, although some lineages such as COAD and HNSC show a favorable association.

COAD, CCRCC, and HNSC are the cancer types where ZC3H15 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	1.000	0.865	.044	12	view →
CCRCC	OS	Median	All	0.906	0.982	.029	7	view →
HNSC	OS	Median	All	1.000	0.960	.026	7	view →
LUAD	OS	Tertile	II,III,IV	0.361	0.871	.022	7	view →
LSCC	OS	Tertile	All	1.000	0.918	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ZC3H15–COAD (DFS)

Open the COAD breakdown →