ZC3H15

Across TCGA patient cohorts, ZC3H15 protein abundance is significantly associated with the RNA expression of many other genes, with 12,885 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZC3H15-associated genes across cancer lineages are STEAP4, PSMD14, and NEK2. Each is linked with ZC3H15 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZC3H15-to-partner and partner-to-ZC3H15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZC3H15 versus STEAP4 in BRCA, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H15→partner) and Y-score (partner→ZC3H15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	STEAP4 →	-1.314	-0.208	<.001	<.001	3	6
HNSC	PSMD14 →	+0.482	+0.234	<.001	<.001	2	6
BRCA	NEK2 →	+0.882	+0.239	.001	.001	3	5
CCRCC	GALNT15 →	-1.205	-0.225	<.001	<.001	3	5
OV	OLA1 →	+0.619	+0.363	<.001	<.001	3	5
LSCC	NUF2 →	+0.918	+0.295	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,885 associations by consensus.

ZC3H15 vs STEAP4 — BRCA

Explore this scatter interactively →