ZC3H15

Across TCGA patient cohorts, ZC3H15 mutation is significantly associated with the RNA expression of many other genes, with 1,293 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZC3H15-associated genes across cancer lineages are RNU6-117P, MEMO1P4, and RN7SL91P. Each is linked with ZC3H15 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZC3H15-to-partner and partner-to-ZC3H15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-117P grouped by ZC3H15-low versus ZC3H15-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H15→partner) and Y-score (partner→ZC3H15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-117P →	+0.408	+4.902	<.001	<.001	3	2
BRCA	MEMO1P4 →	+0.157	+4.396	<.001	.002	3	2
BRCA	RN7SL91P →	+0.090	+4.683	.001	.005	3	2
BRCA	TUBBP11 →	+0.103	+5.201	<.001	.002	3	2
CESC	PNPT1P2 →	+0.031	+5.306	<.001	.006	3	2
SKCM	IL9 →	+0.421	+5.037	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,293 associations by consensus.

RNU6-117P by ZC3H15 expression — BRCA

Explore this box plot interactively →