ZC3H12B

Across TCGA patient cohorts, ZC3H12B RNA expression is significantly associated with the protein abundance of many other proteins, with 14,875 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ZC3H12B-associated proteins across cancer lineages are ADD3, DDAH2, and HDGFL3. Each is linked with ZC3H12B in more than 4 cancer types. Because this analysis shows association rather than direction, both ZC3H12B-to-partner and partner-to-ZC3H12B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZC3H12B versus ADD3 in HNSC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H12B→partner) and Y-score (partner→ZC3H12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ADD3 →	+0.349	+0.390	<.001	.001	3	5
PDAC	DDAH2 →	+0.502	+0.551	<.001	<.001	3	5
GBM	HDGFL3 →	+0.550	+0.631	<.001	.001	3	5
BRCA	LMCD1 →	+0.516	+0.309	<.001	<.001	3	5
PDAC	SEPTIN7 →	+0.221	+0.304	<.001	<.001	3	5
UCEC	TMOD2 →	+0.568	+0.827	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,875 associations by consensus.

ZC3H12B vs ADD3 — HNSC

Explore this scatter interactively →