ZC3H12B

Across TCGA patient cohorts, ZC3H12B protein abundance is significantly associated with the RNA expression of many other genes, with 320 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZC3H12B-associated genes across cancer lineages are NECTIN1, ACCS, and RTN4. Each is linked with ZC3H12B in more than 1 cancer types. Because this analysis shows association rather than direction, both ZC3H12B-to-partner and partner-to-ZC3H12B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZC3H12B versus NECTIN1 in GBM, with a Pearson correlation of 0.87.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H12B→partner) and Y-score (partner→ZC3H12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NECTIN1 →	+1.357	+0.611	.002	.009	3	1
GBM	ACCS →	-0.946	-0.621	.005	.007	3	1
GBM	RTN4 →	+0.789	+0.610	.003	.009	3	1
GBM	GNLY →	+1.366	+0.610	.003	.009	3	1
GBM	RAB33A →	+2.298	+0.610	.002	.009	3	1
GBM	AGTPBP1 →	+1.088	+0.610	.004	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 320 associations by consensus.

ZC3H12B vs NECTIN1 — GBM

Explore this scatter interactively →