ZC3H12B

Across TCGA cell cohorts, ZC3H12B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,542 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZC3H12B-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, Subtelomeric heterochromatin formation, and Positive regulation of DNA repair. Each is linked with ZC3H12B in more than 11 cancer types. Because this analysis shows association rather than direction, both ZC3H12B-to-partner and partner-to-ZC3H12B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair grouped by ZC3H12B-low versus ZC3H12B-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H12B→partner) and Y-score (partner→ZC3H12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of double-strand break repair →	+0.077	+0.790	<.001	<.001	3	12
BONE	Subtelomeric heterochromatin formation →	+0.119	+0.670	<.001	<.001	3	12
OVARY	Positive regulation of DNA repair →	+0.064	+0.900	<.001	<.001	3	12
LUNG_SCLC	Transport along microtubule →	+0.058	+0.653	.003	.002	2	12
BLOOD_Lymphoma	Regulation of organelle assembly →	+0.040	+0.510	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of double-strand break repair →	+0.063	+0.164	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,542 associations by consensus.

Positive regulation of double-strand break repair by ZC3H12B expression — OVARY

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