ZC3H12B

Across TCGA cell cohorts, ZC3H12B mutation is significantly associated with the RNA expression of many other genes, with 853 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZC3H12B-associated genes across cancer lineages are CD300H, ANKRD54, and CCDC134. Each is linked with ZC3H12B in more than 1 cancer types. Because this analysis shows association rather than direction, both ZC3H12B-to-partner and partner-to-ZC3H12B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300H grouped by ZC3H12B-low versus ZC3H12B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H12B→partner) and Y-score (partner→ZC3H12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CD300H →	+0.016	+2.678	<.001	.005	3	2
LARGE_INTESTINE	ANKRD54 →	+0.530	+2.588	<.001	.004	3	1
LARGE_INTESTINE	CCDC134 →	+0.764	+3.301	.001	.003	3	1
LARGE_INTESTINE	CBY1 →	+0.613	+3.714	<.001	<.001	3	1
LARGE_INTESTINE	JOSD1 →	+0.504	+3.169	.005	.009	3	1
LARGE_INTESTINE	MCAT →	+0.674	+3.169	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 853 associations by consensus.

CD300H by ZC3H12B expression — LARGE_INTESTINE

Explore this box plot interactively →