ZC3H10

Across TCGA patient cohorts, ZC3H10 protein abundance is significantly associated with the RNA expression of many other genes, with 1,428 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZC3H10-associated genes across cancer lineages are DDIT4L, HIRA, and LRRC75A. Each is linked with ZC3H10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZC3H10-to-partner and partner-to-ZC3H10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZC3H10 versus DDIT4L in GBM, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H10→partner) and Y-score (partner→ZC3H10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DDIT4L →	+1.179	+0.382	<.001	.001	3	2
PDAC	HIRA →	-0.346	-0.704	.002	<.001	3	2
BRCA	LRRC75A →	+0.450	+0.410	.008	.003	3	2
BRCA	ZNF34 →	+0.567	+0.500	.005	.002	3	2
BRCA	TADA2A →	+0.653	+0.550	<.001	<.001	3	2
UCEC	ZNF639 →	+0.328	+0.186	.007	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,428 associations by consensus.

ZC3H10 vs DDIT4L — GBM

Explore this scatter interactively →