ZC3H10

Across TCGA patient cohorts, ZC3H10 mutation is significantly associated with the RNA expression of many other genes, with 1,817 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZC3H10-associated genes across cancer lineages are RNU1-17P, ATP6V0E1P3, and RNU6-1247P. Each is linked with ZC3H10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZC3H10-to-partner and partner-to-ZC3H10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-17P grouped by ZC3H10-low versus ZC3H10-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H10→partner) and Y-score (partner→ZC3H10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU1-17P →	+0.219	+5.103	<.001	.008	3	2
BLCA	ATP6V0E1P3 →	+0.217	+4.719	<.001	.003	3	2
BLCA	RNU6-1247P →	+0.561	+4.926	<.001	.002	3	2
UCEC	MIR3912 →	+0.336	+2.638	<.001	<.001	3	2
BLCA	SNORD116-10 →	+0.228	+5.289	<.001	.003	3	2
COAD	MIR4472-2 →	+0.711	+5.893	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,817 associations by consensus.

RNU1-17P by ZC3H10 expression — CESC

Explore this box plot interactively →