ZC2HC1B

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZC2HC1B mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZC2HC1B-associated genes across cancer lineages are CMP and Neurons. Each is linked with ZC2HC1B in more than 1 cancer types. Because this analysis shows association rather than direction, both ZC2HC1B-to-partner and partner-to-ZC2HC1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CMP grouped by ZC2HC1B-low versus ZC2HC1B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC2HC1B→partner) and Y-score (partner→ZC2HC1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCMP →-0.045-3.159.007.02011
UCECNeurons →-0.025-3.148.016.02011
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CMP by ZC2HC1B expression — UCEC

Box plot of CMP in ZC2HC1B-low vs ZC2HC1B-high samples in UCEC.

Explore this box plot interactively →

Exploration