ZC2HC1A

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZC2HC1A mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZC2HC1A-associated genes across cancer lineages are OR10W1 and CD300H. Each is linked with ZC2HC1A in more than 1 cancer types. Because this analysis shows association rather than direction, both ZC2HC1A-to-partner and partner-to-ZC2HC1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by ZC2HC1A-low versus ZC2HC1A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC2HC1A→partner) and Y-score (partner→ZC2HC1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEOR10W1 →+0.015+4.977<.001.00731
LARGE_INTESTINECD300H →+0.045+5.415<.001.00431
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR10W1 by ZC2HC1A expression — LARGE_INTESTINE

Box plot of OR10W1 in ZC2HC1A-low vs ZC2HC1A-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration