Across TCGA patient cohorts, ZBTB9 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB9-associated genes across cancer lineages are MSH2, p27_pT198, and VHL. Each is linked with ZBTB9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB9-to-partner and partner-to-ZBTB9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB9→partner) and Y-score (partner→ZBTB9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MSH2 →	-0.347	-2.973	.001	.035	3	2
UCEC	p27_pT198 →	+0.114	+3.321	.028	.010	3	2
UCEC	VHL →	-0.980	-3.321	.002	.010	3	2
UCEC	YB-1 →	+0.182	+2.486	.017	.011	3	2
UCEC	14-3-3_beta →	-0.107	-2.973	.028	.035	3	1
UCEC	eIF4G →	+0.323	+2.459	.031	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

ZBTB9 survival (RNA) · tumor vs normal (RNA) · all ZBTB9 data types