Across TCGA cell cohorts, ZBTB9 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZBTB9-associated genes across cancer lineages are CFHR2, HOXB1, and CRISP2. Each is linked with ZBTB9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB9-to-partner and partner-to-ZBTB9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB9→partner) and Y-score (partner→ZBTB9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CFHR2 →	+0.245	+5.124	<.001	<.001	3	2
LARGE_INTESTINE	HOXB1 →	+0.025	+3.376	<.001	<.001	3	1
LARGE_INTESTINE	CRISP2 →	+0.010	+2.882	.006	.005	3	1
BLOOD_Leukemia	KLRD1 →	+0.283	+3.769	<.001	.008	3	1
BLOOD_Leukemia	KAAG1 →	+0.093	+3.855	<.001	.007	3	1
BLOOD_Leukemia	ASZ1 →	+0.120	+4.567	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

ZBTB9 survival (RNA) · tumor vs normal (RNA) · all ZBTB9 data types