ZBTB8OS

Across TCGA pan-cancer cohorts, ZBTB8OS Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ZBTB8OS data layer compared with 24 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher ZBTB8OS Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZBTB8OS expression acts as an unfavorable survival marker.

BRCA and KIRP are the cancer types where ZBTB8OS Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Median	All	0.753	0.950	.002	23	view →
KIRP	OS	Median	All	0.111	0.702	.001	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

ZBTB8OS–BRCA (DFS)

Open the BRCA breakdown →