ZBTB8OS

Across TCGA cell cohorts, ZBTB8OS RNA expression is significantly associated with the go_rna of many other GO terms, with 2,756 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZBTB8OS-associated GO terms across cancer lineages are mRNA splicing, via endonucleolytic cleavage and ligation, RNA exon ligation, and tRNA exon ligation. Each is linked with ZBTB8OS in more than 18 cancer types. Because this analysis shows association rather than direction, both ZBTB8OS-to-partner and partner-to-ZBTB8OS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA splicing, via endonucleolytic cleavage and ligation grouped by ZBTB8OS-low versus ZBTB8OS-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB8OS→partner) and Y-score (partner→ZBTB8OS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	mRNA splicing, via endonucleolytic cleavage and ligation →	+0.172	+0.953	<.001	<.001	3	19
LUNG_SCLC	RNA exon ligation →	+0.132	+0.880	<.001	<.001	3	16
LUNG_SCLC	tRNA exon ligation →	+0.132	+0.880	<.001	<.001	3	16
LUNG_NSCLC_LUAD	Iron-sulfur cluster assembly →	+0.071	+0.581	<.001	.002	3	7
LUNG_NSCLC_LUAD	Metallo-sulfur cluster assembly →	+0.071	+0.581	<.001	.002	3	7
OVARY	7-methylguanosine cap hypermethylation →	+0.085	+0.572	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,756 associations by consensus.

mRNA splicing, via endonucleolytic cleavage and ligation by ZBTB8OS expression — KIDNEY

Explore this box plot interactively →