Across TCGA cell cohorts, ZBTB7C mutation is significantly associated with the RNA expression of many other genes, with 361 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZBTB7C-associated genes across cancer lineages are OR6P1, GSKIP, and OXSM. Each is linked with ZBTB7C in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB7C-to-partner and partner-to-ZBTB7C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB7C→partner) and Y-score (partner→ZBTB7C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR6P1 →	+0.004	+2.786	.002	.009	3	2
LARGE_INTESTINE	GSKIP →	+0.661	+2.244	.003	.003	3	2
LARGE_INTESTINE	OXSM →	+0.565	+2.000	.002	.009	3	2
LARGE_INTESTINE	GLOD4 →	+0.538	+3.169	.002	.009	3	2
LARGE_INTESTINE	IKBKE →	-0.820	-2.764	.002	.001	3	2
CNS	AWAT2 →	+0.213	+3.832	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 361 associations by consensus.

Exploration

ZBTB7C survival (RNA) · tumor vs normal (RNA) · all ZBTB7C data types