Across TCGA patient cohorts, ZBTB6 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB6-associated genes across cancer lineages are Annexin-1, ASNS, and c-Kit. Each is linked with ZBTB6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB6-to-partner and partner-to-ZBTB6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB6→partner) and Y-score (partner→ZBTB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.512	+3.584	.011	.002	3	2
UCEC	ASNS →	+0.388	+2.459	.005	.018	3	2
UCEC	c-Kit →	-0.181	-1.678	.042	.023	3	2
UCEC	EGFR →	-0.163	-3.143	.007	.018	3	1
UCEC	ACC1 →	+0.307	+2.183	.027	.033	3	1
UCEC	JNK_pT183_Y185 →	-0.157	-1.664	.015	.023	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

ZBTB6 survival (RNA) · tumor vs normal (RNA) · all ZBTB6 data types