ZBTB6

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZBTB6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,003 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZBTB6-associated GO terms across cancer lineages are Proteasome regulatory particle assembly, Regulation of heterochromatin organization, and Positive regulation of RNA splicing. Each is linked with ZBTB6 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZBTB6-to-partner and partner-to-ZBTB6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB6→partner) and Y-score (partner→ZBTB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCProteasome regulatory particle assembly →+0.144+0.763<.001<.001314
LUNG_SCLCRegulation of heterochromatin organization →+0.122+0.593<.001<.001314
STOMACHPositive regulation of RNA splicing →+0.113+1.041<.001<.001314
STOMACHProtein localization to nucleus →+0.068+0.675<.001.004314
STOMACHVesicle tethering →+0.084+0.784<.001<.001314
LUNG_SCLCRegulation of organelle assembly →+0.054+0.684<.001.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,003 associations by consensus.

Exploration