ZBTB6

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZBTB6 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ZBTB6-associated genes across cancer lineages are OOSP2, OR10J5, and OR10J1. Each is linked with ZBTB6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB6-to-partner and partner-to-ZBTB6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB6→partner) and Y-score (partner→ZBTB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTOOSP2 →+0.023+5.781<.001.00131
BREASTOR10J5 →+0.071+5.169<.001.00531
BREASTOR10J1 →+0.566+5.781<.001.00131
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration