ZBTB5

Across TCGA patient cohorts, ZBTB5 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,090 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZBTB5-associated proteins across cancer lineages are WDR5, SMC1A, and SMC3. Each is linked with ZBTB5 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZBTB5-to-partner and partner-to-ZBTB5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZBTB5 versus WDR5 in LSCC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB5→partner) and Y-score (partner→ZBTB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WDR5 →	+0.355	+0.831	<.001	<.001	3	7
GBM	SMC1A →	+0.315	+0.384	<.001	.004	3	6
BRCA	SMC3 →	+0.282	+0.495	<.001	.001	3	6
GBM	NELFE →	+0.282	+0.496	<.001	<.001	3	6
BRCA	PSIP1 →	+0.709	+0.646	<.001	<.001	3	6
GBM	SMU1 →	+0.252	+0.489	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,090 associations by consensus.

ZBTB5 vs WDR5 — LSCC

Explore this scatter interactively →