ZBTB5

Across TCGA cell cohorts, ZBTB5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,494 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZBTB5-associated GO terms across cancer lineages are Nucleic acid catabolic process, Protein sumoylation, and Positive regulation of mRNA metabolic process. Each is linked with ZBTB5 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZBTB5-to-partner and partner-to-ZBTB5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleic acid catabolic process grouped by ZBTB5-low versus ZBTB5-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB5→partner) and Y-score (partner→ZBTB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Nucleic acid catabolic process →	+0.061	+1.128	<.001	<.001	3	15
STOMACH	Protein sumoylation →	+0.092	+0.791	.001	.005	3	15
LARGE_INTESTINE	Positive regulation of mRNA metabolic process →	+0.064	+0.703	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Regulation of nucleotide-excision repair →	+0.116	+1.685	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Spliceosomal complex assembly →	+0.086	+1.311	<.001	.003	3	15
LARGE_INTESTINE	Nucleic acid transport →	+0.099	+0.921	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,494 associations by consensus.

Nucleic acid catabolic process by ZBTB5 expression — STOMACH

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