ZBTB49

Across TCGA cell cohorts, ZBTB49 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,463 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZBTB49-associated GO terms across cancer lineages are Regulation of organelle assembly, Positive regulation of organelle assembly, and Positive regulation of CAMKK-AMPK signaling cascade. Each is linked with ZBTB49 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZBTB49-to-partner and partner-to-ZBTB49 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of organelle assembly grouped by ZBTB49-low versus ZBTB49-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB49→partner) and Y-score (partner→ZBTB49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of organelle assembly →	+0.047	+0.608	<.001	<.001	3	16
STOMACH	Positive regulation of organelle assembly →	+0.080	+1.063	.001	<.001	3	15
PANCREAS	Positive regulation of CAMKK-AMPK signaling cascade →	+0.393	+0.362	.003	<.001	3	15
STOMACH	Heterochromatin formation →	+0.093	+0.898	<.001	.001	3	15
BONE	Negative regulation of gene expression, epigenetic →	+0.080	+0.432	.002	.007	1	17
OESOPHAGUS	Nuclear-transcribed mRNA catabolic process →	+0.074	+0.641	.001	.002	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,463 associations by consensus.

Regulation of organelle assembly by ZBTB49 expression — LARGE_INTESTINE

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