Across TCGA patient cohorts, ZBTB48 protein abundance is significantly associated with the protein abundance of many other proteins, with 3,653 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZBTB48-associated proteins across cancer lineages are ZBTB40, RMDN2_S121, and ZC3H13_S370. Each is linked with ZBTB48 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZBTB48-to-partner and partner-to-ZBTB48 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB48→partner) and Y-score (partner→ZBTB48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZBTB40 →	+0.339	+0.472	<.001	.003	3	2
PDAC	RMDN2_S121 →	-0.752	-0.302	<.001	.002	3	2
LSCC	ZC3H13_S370 →	+0.930	+0.339	.001	<.001	3	1
LSCC	ZC3H3_S414 →	+0.997	+0.406	<.001	.002	3	1
LSCC	ZC3H4 →	+0.191	+0.288	.002	.001	3	1
LSCC	ZCCHC17 →	+0.200	+0.181	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,653 associations by consensus.

Exploration

ZBTB48 survival (RNA) · tumor vs normal (RNA) · all ZBTB48 data types