Across TCGA patient cohorts, ZBTB48 mutation is significantly associated with the RNA expression of many other genes, with 857 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB48-associated genes across cancer lineages are RNU6-1055P, IGLVVI-25-1, and KIR2DL1. Each is linked with ZBTB48 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB48-to-partner and partner-to-ZBTB48 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB48→partner) and Y-score (partner→ZBTB48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RNU6-1055P →	+0.825	+6.305	<.001	.001	3	2
BLCA	IGLVVI-25-1 →	+0.082	+4.455	<.001	.005	3	2
BLCA	KIR2DL1 →	+0.317	+3.643	.003	.005	3	2
HNSC	CYTH1P1 →	+0.156	+4.452	<.001	.006	3	2
LUSC	LINC02414 →	+0.118	+4.370	.001	.002	3	2
UCEC	HYI-AS1 →	+0.441	+2.243	.007	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 857 associations by consensus.

Exploration

ZBTB48 survival (RNA) · tumor vs normal (RNA) · all ZBTB48 data types