Across TCGA patient cohorts, ZBTB48 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB48-associated genes across cancer lineages are FoxM1, Notch1, and PDCD4. Each is linked with ZBTB48 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB48-to-partner and partner-to-ZBTB48 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB48→partner) and Y-score (partner→ZBTB48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.292	+2.321	.024	.035	3	1
UCEC	Notch1 →	+0.230	+3.459	.001	.005	3	1
UCEC	PDCD4 →	-0.496	-2.321	.036	.035	3	1
UCEC	STAT3_pY705 →	-0.453	-2.321	<.001	.035	3	1
UCEC	Tuberin_pT1462 →	+0.296	+2.179	.010	.034	3	1
UCEC	VHL →	-0.988	-3.000	.003	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

ZBTB48 survival (RNA) · tumor vs normal (RNA) · all ZBTB48 data types