Across TCGA cell cohorts, ZBTB48 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZBTB48-associated genes across cancer lineages are GABRA4, PNMA6F, and C6orf118. Each is linked with ZBTB48 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB48-to-partner and partner-to-ZBTB48 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB48→partner) and Y-score (partner→ZBTB48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	GABRA4 →	+0.119	+4.035	<.001	.003	3	1
OVARY	PNMA6F →	+0.008	+3.754	<.001	.002	3	1
LARGE_INTESTINE	C6orf118 →	+0.116	+4.115	<.001	.001	3	1
LARGE_INTESTINE	SSMEM1 →	+0.021	+4.029	.007	.002	3	1
LARGE_INTESTINE	PROP1 →	+0.033	+4.376	<.001	<.001	3	1
LARGE_INTESTINE	ELOA3DP →	+0.027	+3.688	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

ZBTB48 survival (RNA) · tumor vs normal (RNA) · all ZBTB48 data types