ZBTB47

Across TCGA pan-cancer cohorts, ZBTB47 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ZBTB47 data layer compared with 27 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher ZBTB47 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ZBTB47 expression acts as an unfavorable survival marker.

LSCC, CCRCC, and HNSC are the cancer types where ZBTB47 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	II,III,IV	0.860	1.000	.009	15	view →
CCRCC	DFS	Median	All	0.095	0.740	.006	15	view →
HNSC	OS	Median	All	0.645	0.944	.032	2	view →
LUAD	OS	Quartile	All	0.361	0.880	.025	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ZBTB47–LSCC (OS)

Open the LSCC breakdown →