ZBTB47

Across TCGA patient cohorts, ZBTB47 mutation is significantly associated with the RNA expression of many other genes, with 3,747 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB47-associated genes across cancer lineages are RBISP1, LINC02485, and LINC00261. Each is linked with ZBTB47 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB47-to-partner and partner-to-ZBTB47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBISP1 grouped by ZBTB47-low versus ZBTB47-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB47→partner) and Y-score (partner→ZBTB47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RBISP1 →	+0.123	+3.595	<.001	.005	3	2
UCEC	LINC02485 →	+0.102	+1.470	.007	.002	3	2
UCEC	LINC00261 →	+1.162	+2.818	.003	.001	3	2
CESC	TTTY9B →	+0.016	+5.263	<.001	.001	3	1
CESC	RN7SKP124 →	+0.249	+4.142	<.001	.001	3	1
CESC	TCL1B →	+0.162	+3.431	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,747 associations by consensus.

RBISP1 by ZBTB47 expression — CESC

Explore this box plot interactively →