ZBTB47

Across TCGA cell cohorts, ZBTB47 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZBTB47-associated genes across cancer lineages are LYZL2, C14orf177, and TAAR8. Each is linked with ZBTB47 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB47-to-partner and partner-to-ZBTB47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LYZL2 grouped by ZBTB47-low versus ZBTB47-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB47→partner) and Y-score (partner→ZBTB47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LYZL2 →	+0.033	+6.569	<.001	<.001	3	1
BLOOD_Leukemia	C14orf177 →	+0.052	+4.922	.001	.009	3	1
LUNG_NSCLC_LUAD	TAAR8 →	+0.017	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	UBQLN3 →	+0.006	+4.734	.002	.002	3	1
LARGE_INTESTINE	C6orf118 →	+0.130	+3.115	<.001	.004	3	1
LARGE_INTESTINE	VCY1B →	+0.701	+4.199	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

LYZL2 by ZBTB47 expression — BLOOD_Leukemia

Explore this box plot interactively →