ZBTB45

Across TCGA patient cohorts, ZBTB45 mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB45-associated genes across cancer lineages are Erythrocytes, Monocytes, and Preadipocytes. Each is linked with ZBTB45 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZBTB45-to-partner and partner-to-ZBTB45 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Erythrocytes grouped by ZBTB45-low versus ZBTB45-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB45→partner) and Y-score (partner→ZBTB45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Erythrocytes →	+0.022	+3.180	.021	.010	3	3
COAD	Monocytes →	+0.048	+5.734	<.001	.027	3	1
COAD	Preadipocytes →	+0.075	+4.169	<.001	.027	3	1
UCEC	Epithelial cells →	-0.065	-1.678	.017	.023	3	1
UCEC	NKT →	-0.084	-3.448	.039	.005	3	1
UCEC	Plasma cells →	-0.018	-3.186	.030	.011	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Erythrocytes by ZBTB45 expression — UCEC

Explore this box plot interactively →