ZBTB45

Across TCGA cell cohorts, ZBTB45 mutation is significantly associated with the RNA expression of many other genes, with 65 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZBTB45-associated genes across cancer lineages are GALP, KRTAP2-4, and CABP2. Each is linked with ZBTB45 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB45-to-partner and partner-to-ZBTB45 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GALP grouped by ZBTB45-low versus ZBTB45-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB45→partner) and Y-score (partner→ZBTB45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GALP →	+0.025	+3.201	<.001	.005	3	2
SOFT_TISSUE	KRTAP2-4 →	+0.122	+4.930	<.001	.008	3	1
SKIN	CABP2 →	+0.024	+4.022	<.001	.006	3	1
SKIN	OR4S2 →	+0.021	+4.022	<.001	.006	3	1
SKIN	OR2T3 →	+0.008	+4.022	<.001	.006	3	1
SKIN	SLC22A6 →	+0.003	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 65 associations by consensus.

GALP by ZBTB45 expression — BLOOD_Leukemia

Explore this box plot interactively →